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Insulin-Producing Organoids Offer Hope for Treating Type 1 Diabetes
Insulin-Producing Organoids Offer Hope for Treating Type 1 DiabetesPosted on September 24th, 2020 by Dr. Francis CollinsCaption: Human islet-like organoids express insulin (green). For some people with type 1 diabetes, there is another option. Checkpoint inhibitors work by blocking the interaction of PD-1 and PD-L1, freeing up immune cells to fight cancer. Not only did the transplanted HILOs produce insulin in response to glucose spikes, they spurred no immune response. Evans Lab (Salk Institute, La Jolla, CA)NIH Support: National Institute of Diabetes and Digestive and Kidney Diseases; National Cancer Institute
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