Exercise Releases Brain-Healthy ProteinPosted on June 28th, 2016 by Dr. Francis CollinsWe all know that exercise is important for a strong and healthy body. In mice, brain cells treated with the protein also exhibited molecular changes associated with the production of new neurons. The team set out to find proteins that muscle cells secrete during exercise that could be transported to the brain . Sure enough, the study showed a significant increase in blood cathepsin B levels with regular fitness training. And yet, compounds that elevate cathepsin B levels in mouse models of Alzheimer’s disease have been neuroprotective .